SAFETY TESTS
The following safety tests were performed on the raw material ” Methionyl r-Clostridium Botulinum Polypeptide-1 Hexapeptide-40 ”.
- Cell toxicity (in-House Lab.)
- Bacterial Reverse Mutation Assay test (GLP Lab.)
- Chromosomal test (GLP Lab.)
The following additional tests are conducted on the safety of ‘Methionyl r-Clostridium Botulinum Polypeptide-1 Hexapeptide-40’ and animal testing of this ingredient is never carried out.
- Skin Irritation using EPISKIN
- Eye Irritation using EpiOcular test
- Skin Sensitization : Local Lymph node Assay : BrdU-ELISA)
- in vitro 3T3 NRU Photoxity Test
CLINICAL TESTS
Single Human Patch Test
Bolca Anti-Wrinkle Facial Serum
(I.E.C. Korea @ Chonnam National Univ. Hospital)
Clinical Test (I.E.C. Korea)
Bolca Anti-Wrinkle Facial Serum
(I.E.C. Korea)
After 4 weeks test shows improvement of roughness, elasticity, nasolabial line from 70% of applicant. Different from individuals but the efficacy can be seen normally within 2 weeks
Effectivenss | Ratio | |
|---|---|---|
Roughness | 16/22 | 72% |
Net Elasticity | 22/22 | 100% |
Nasolabial line | 15/22 | 68% |